W-54011

W-54011

Dodatkowe informacje:

• SMILES: Cl.O=C(N(C1=CC=C(C=C1)C(C)C)CC2=CC=C(C=C2)N(C)C)C3C4=CC(OC)=CC=C4CCC3
• Formula: C30H37ClN2O2

Specyfikacja/Zawartość:

• Purity: 0.98
• CAS#: 405098-33-1
• Molecular Weight: 493.08
• Bioactivity: W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki = 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils (IC50s = 3.1 nM, 2.7 nM, and 1.6 nM, respectively).

Inne:

For research use only.