Rhesus macaque TROP-2 / TACSTD2 Protein, Fc Tag (MALS verified)

Rhesus macaque TROP-2 Protein, Fc Tag (TR2-R5255) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Thr 274 (Accession # XP_001114599.1).

Dodatkowe informacje:

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

Specyfikacja/Zawartość:

Rhesus macaque

Wysyłka i przechowywanie:

-20℃ RT

Inne:

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53.9 kDa. The protein migrates as 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.