Anti-TXNL4A antibody

The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants.

Specyfikacja/Zawartość:

• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Applications: WB
• Reactivity: Human,Mouse
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purification: Affinity purification
• Clone: NA
• Concentration: NA
• Gene: TXNL4A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1).