MeOSuc-Ala-Ala-Pro-Val-AMC

MeOSuc-Ala-Ala-Pro-Val-AMC

Dodatkowe informacje:

• SMILES: CC=1C=2C(=CC(NC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC(CCC(OC)=O)=O)C)=O)C)=O)CCC3)[C@@H](C)C)=O)=CC2)OC(=O)C1
• Formula: C31H41N5O9

Specyfikacja/Zawartość:

• Purity: 0.98
• CAS#: 72252-90-5
• Molecular Weight: 627.69
• Bioactivity: MeOSuc-Ala-Ala-Pro-Val-AMC (MeOSuc-AAPV-AMC) is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase. The methoxy succinyl (MeO-Suc) peptide AAPV is avidly hydrolyzed by these elastases but not by cathepsin G. The addition of 7-amino-4-methylcoumarin (AMC) generates a peptide of low fluorescence (excitation: 355-380 nm
• emission 440-460 nm) that demonstrates a linear increase in fluorescence in the presence of elastase. This peptidyl-AMC substrate detects as little as 11 pM human leukocyte elastase and 18 pM porcine pancreatic elastase.

Inne:

For research use only.