Anti-Human Follistatin Antibody

Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Human Follistatin is aa 31-33 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.

Specyfikacja/Zawartość:

• Gene name: Follistatin
• Host: Mouse
• Label: None
• Clone: (#9D47)
• Isotype: IgG2
• Applications: Capture Ab
• Species Reactivity/Origin species: Human
• Antigen: Recombinant human Follistatin
• Purification method: Protein G chromatography
• Reconstitution Buffer: PBS
• Buffer: PBS
• Additives/Stabilizer: None
• Form: lyophilized
• Storage: Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
• Reconstitution tips: Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
• NCBI GeneID: 10468
• Accession Number Protein: NP_006341.1
• Accession Numberm RNA: NM_006350
• Uniprot: P19883
• Chromosomal location: 5q11.2

Inne:

For research use only.