5'-chloro-5'-Deoxyadenosine (hydrate)
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5'-chloro-5'-Deoxyadenosine (hydrate)
Dodatkowe informacje:
- SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CCl)[C@H]1O.O
- Formula: C10H14ClN5O4
Specyfikacja/Zawartość:
- Purity: 0.98
- CAS#: 698999-09-6
- Molecular Weight: 303.7
- Bioactivity: 5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5'-adenosyl)-L-methionine can be converted to 5'-chloro-5'-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase. Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A in the marine bacterium S. tropica.
Inne:
For research use only.
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