DMAP1 Rabbit mAb

Recombinant protein of human INSR/IGF1R.

Dodatkowe informacje:

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Specyfikacja/Zawartość:

Monoclonal Antibodies

Wysyłka i przechowywanie:

Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Inne:

Epigenetics Nuclear Signaling,Transcription Factors,Protein phosphorylation,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Inhibition of Apoptosis,Microtubules,Immunology Inflammation,Jak-Stat-IL-6 Receptor Signaling Pathway,Stem Cells,Embryonic Stem Cells,Cardiovascular,Heart,Cardiogenesis,Hypertrophy