DYNLL1 Rabbit mAb

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MSH6 (NP_000170.1).

Dodatkowe informacje:

This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

Specyfikacja/Zawartość:

Monoclonal Antibodies

Wysyłka i przechowywanie:

Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Inne:

Epigenetics Nuclear Signaling,DNA Damage Repair,Cancer,Tumor suppressors,p53 pathway,Invasion and Metastasis,Signal Transduction,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Autophagy,Cytoskeleton,Motor Proteins,Endocrine Metabolism,Neuroscience