CD2 Rabbit mAb

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PSMC5 (NP_002796.4).

Dodatkowe informacje:

• The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits
• 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Specyfikacja/Zawartość:

Monoclonal Antibodies

Wysyłka i przechowywanie:

Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Inne:

Cell Biology Developmental Biology,Apoptosis,Immunology Inflammation,CDs,Stem Cells,Hematopoietic Progenitors