SARS Protein Detection Set
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A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral S (Spike) protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. The M protein (Membrane protein, Matrix protein) is another major structural viral protein. It is an integral membrane protein involved in the budding of the viral particles and interacts with S protein and the nucleocapsid protein. The SARS E protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. ACE2, the SARS receptor, normally plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis.;;For images please see PDF data sheet
Dodatkowe informacje:
Optimal dilutions for each application to be determined by the researcher.
Specyfikacja/Zawartość:
- Host Species: N/A
- Species Reactivity: Human
- Homology: N/A
- Immunogen: Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.
- Tested Applications: WB, IHC, IF
- Applications: N/A
- Specificity: N/A
- Purification: Antibodies are supplied as affinity chromatography purified IgG.
- Clonality: Polyclonal
- Isotype: N/A
- Conjugate: N/A
- Physical State: Liquid
- Buffer: PBS containing 0.02% sodium azide.
- Concentration: Antibody 1 mg/mL
- Peptide 200 µg/mL
- Set Contents: ACE2 Antibody (IN1), Catalog No. 3215 (50 µg). SARS Envelope Antibody (CT), Catalog No. 3533 (50 µg). SARS Matrix Antibody (CT), Catalog No. 3529 (50 µg). SARS Spike Antibody (CT), Catalog No. 3525 (50 µg). SARS Envelope Peptide (CT), Catalog No. 3533P. SARS Matrix Peptide (CT), Catalog No. 3529P. SARS Spike Peptide (CT), Catalog No. 3525P
- Products: 3215, 3533, 3529 , 3525, 3533P, 3529P, 3525P
Wysyłka i przechowywanie:
- Stable at 4°C for three months, store at -20°C for up to one year.
- Shipping Condition: Not Specified
Inne:
For Research Use Only
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