PRRT2 Antibody

PRRT2 Antibody: The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.

Dodatkowe informacje:

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Specyfikacja/Zawartość:

• Research area: Stem Cell
• Host species: Rabbit
• Species reactivity: Human, Mouse, Rat
• Homology: N/A
• Immunogen: PRRT2 antibody was raised against a 18 amino acid peptide near the center of human PRRT2 .
• The immunogen is located within amino acids 180 - 230 of PRRT2.
• Tested Applications: E, WB, IHC-P, IF
• Applications: PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 μ
• g/mL.
• Antibody validated: Western Blot in mouse samples
• Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
• Specificity: Multiple isoforms of PRRT2 are known to exist.
• Positive control 1: Cat. No. 1403 - Mouse Brain Tissue Lysate
• Positive control 2: N/A
• Positive control 3: N/A
• Positive control 4: N/A
• Positive control 5: N/A
• Positive control 6: N/A
• Predicted molecular weight: Predicted: 43 kDa
• Observed: 44 kDa
• MW explanation: N/A
• Validation: N/A
• Isoforms: N/A
• Purification: PRRT2 Antibody is affinity chromatography purified via peptide column.
• Clonality: Polyclonal
• Clone: N/A
• Isotype: IgG
• Conjugate: Unconjugated
• Physical state: Liquid
• Buffer: PRRT2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL
• NCBI official symbol: PRRT2
• Accession #: NP_001243371
• Protein GI #: 374253783
• NCBI gene ID#: 112476
• NCBI official full name: proline-rich transmembrane protein 2
• NCBI organism: homo sapiens
• SWISSPROT #: Q7Z6L0

Wysyłka i przechowywanie:

• PRRT2 antibody can be stored at 4˚
• C for three months and -20˚
• C, stable for up to one year.

Inne:

Optimal dilutions for each application to be determined by the researcher.