TSC22D3 Antibody

TSC22D3 Antibody: The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-κB and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-κB. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.

Dodatkowe informacje:

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Specyfikacja/Zawartość:

• Research area: Stem Cell
• Host species: Rabbit
• Species reactivity: Human, Mouse
• Homology: N/A
• Immunogen: Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3.
• The immunogen is located within amino acids 40 - 90 of TSC22D3.
• Tested Applications: E, WB, IHC-P, IF
• Applications: TSC22D3 antibody can be used for detection of TSC22D3 by Western blot at 1 - 2 μ
• g/mL.
• Antibody validated: Western Blot in human samples
• Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
• Specificity: N/A
• Positive control 1: Cat. No. 1308 - Human Small Intestine Tissue Lysate
• Positive control 2: Cat. No. 11-801 - Human Small Intestine Tissue Slide
• Positive control 3: N/A
• Positive control 4: N/A
• Positive control 5: N/A
• Positive control 6: N/A
• Predicted molecular weight: Predicted: 22 kDa
• Observed: 23 kDa
• MW explanation: N/A
• Validation: N/A
• Isoforms: N/A
• Purification: TSC22D3 Antibody is affinity chromatography purified via peptide column.
• Clonality: Polyclonal
• Clone: N/A
• Isotype: IgG
• Conjugate: Unconjugated
• Physical state: Liquid
• Buffer: TSC22D3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL
• NCBI official symbol: TSC22D3
• Accession #: NP_932174
• Protein GI #: 37622903
• NCBI gene ID#: 1831
• NCBI official full name: TSC22 domain family, member 3
• NCBI organism: homo sapiens
• SWISSPROT #: Q99576

Wysyłka i przechowywanie:

• TSC22D3 antibody can be stored at 4˚
• C for three months and -20˚
• C, stable for up to one year.

Inne:

Optimal dilutions for each application to be determined by the researcher.