SCF Recombinant Protein

Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: This recombinant proteins is for research use only.
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 µg/ml in sterile PBS.
• Concentration: N/A
• NCBI official symbol: Kitl
• Accession #: AAH11322
• Protein GI: 15030139
• NCBI gene ID#: 17311
• NCBI official full name: kit ligand
• NCBI organism: Mus musculus
• Peptide sequence: N/A
• SWISSPROT #: O35516
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: CHO cells
• Species: Mouse
• By Source: CHO Cells
• By Species: Mouse
• Fusion tag: Fc Tag
• Sequence: The extracellular domain of mouse SCF (aa 26-214) is fused to the N-terminus of the Fc region of mouse IgG2a.
• Biology activity: N/A
• Purity: >98% (SDS-PAGE).
• Endotoxin level is less than 0.06EU/ µg protein (LAL test
• Lonza).

Wysyłka i przechowywanie:

Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Inne:

Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.