FGF-Basic Recombinant Protein

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant murine FGF-basic is a 16.2 kDa protein consisting of 145 amino acid residues.

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: N/A
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: N/A
• Concentration: N/A
• NCBI official symbol: Fgf2
• Accession #: NP_032032.1
• Protein GI: 7106315
• NCBI gene ID#: 14173
• NCBI official full name: fibroblast growth factor 2
• NCBI organism: Mus musculus
• Peptide sequence: MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
• SWISSPROT #: P15655
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: E. coli
• Species: Murine
• By Source: E. Coli
• By Species: Mouse
• Fusion tag: N/A
• Sequence: MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
• Biology activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is = 1.0 ng/mL, corresponding to a specific activity of = 1 x 10⁶ units/mg.
• Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.

Wysyłka i przechowywanie:

The lyophilized FGF-Basic recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted FGF-Basic is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing FGF-Basic recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Inne:

This product is for research use only.