Dectin-1 Recombinant Protein

Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: This recombinant proteins is for research use only.
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: Contains PBS. Reconstitute with 50 µl sterile water.
• Concentration: 1mg/ml after reconstitution.
• NCBI official symbol: Clec7a
• Accession #: Q6QLQ4
• Protein GI: 408360305
• NCBI gene ID#: 56644
• NCBI official full name: C-type lectin domain family 7, member a
• NCBI organism: Mus musculus
• Peptide sequence: N/A
• SWISSPROT #: P19838
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: HEK293 cells
• Species: Mouse
• By Source: Human Cells
• By Species: Mouse
• Fusion tag: Fc Tag
• Sequence: Mouse dectin-1 (aa 72-244) is fused at the C-terminus to the Fc portion of human IgG1.
• Biology activity: N/A
• Purity: >95% (SDS-PAGE).
• Endotoxin level is less than 0.01EU/ µg purified protein (LAL test
• Lonza).

Wysyłka i przechowywanie:

Stable for at least 6 months after receipt when stored at -20°C.

Inne:

Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.