CTRP5 Recombinant Protein

CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: This recombinant proteins is for research use only.
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: Lyophilized from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Reconstitute in distilled water.
• Concentration: N/A
• NCBI official symbol: C1QTNF5
• Accession #: Q9BXJ0
• Protein GI: 37181891
• NCBI gene ID#: 114902
• NCBI official full name: C1q and tumor necrosis factor related protein 5
• NCBI organism: Homo sapiens
• Peptide sequence: N/A
• SWISSPROT #: P27797
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: E. coli
• Species: Human
• By Source: E. Coli
• By Species: Human
• Fusion tag: His Tag
• Sequence: Human CTRP5 (aa 16-243) is fused at the N-terminus to a His-tag.
• Biology activity: N/A
• Purity: >90% (SDS-PAGE).
• Endotoxin level is less than 1EU/ µg purified protein (LAL test
• Lonza).

Wysyłka i przechowywanie:

Working aliquots are stable for up to 3 months when stored at -20°C.

Inne:

Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.