RANTES Recombinant Protein

RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant murine RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: N/A
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: N/A
• Concentration: N/A
• NCBI official symbol: Ccl5
• Accession #: NP_038681.2
• Protein GI: 164698428
• NCBI gene ID#: 20304
• NCBI official full name: chemokine (C-C motif) ligand 5
• NCBI organism: Mus musculus
• Peptide sequence: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
• SWISSPROT #: P30882
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: E. coli
• Species: Murine
• By Source: E. Coli
• By Species: Mouse
• Fusion tag: N/A
• Sequence: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
• Biology activity: Biological activity was determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10-30 ng/ml.
• Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
• Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Wysyłka i przechowywanie:

The lyophilized RANTES recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted RANTES is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing RANTES recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Inne:

This product is for research use only.