IFN lambda 2 Recombinant Protein

IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces anti-viral defense similar but distinct than the type I Interferons. Recombinant murine IFN-lambda2 is a 19.8 kDa protein containing 175 amino acid residues.

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: N/A
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: N/A
• Concentration: N/A
• NCBI official symbol: Ifnl2
• Accession #: NP_001019844.2
• Protein GI: 130494425
• NCBI gene ID#: 330496
• NCBI official full name: interferon lambda 2
• NCBI organism: Mus musculus
• Peptide sequence: MDPVPRATRL PVEAKDCHIA QFKSLSPKEL QAFKKAKDAI EKRLLEKDMR CSSHLISRAW DLKQLQVQER PKALQAEVAL TLKVWENMTD SALATILGQP LHTLSHIHSQ LQTCTQLQAT AEPKPPSRRL SRWLHRLQEA QSKETPGCLE DSVTSNLFRL LTRDLKCVAS GDQCV
• SWISSPROT #: Q4VK74
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: E. coli
• Species: Murine
• By Source: E. Coli
• By Species: Mouse
• Fusion tag: N/A
• Sequence: MDPVPRATRL PVEAKDCHIA QFKSLSPKEL QAFKKAKDAI EKRLLEKDMR CSSHLISRAW DLKQLQVQER PKALQAEVAL TLKVWENMTD SALATILGQP LHTLSHIHSQ LQTCTQLQAT AEPKPPSRRL SRWLHRLQEA QSKETPGCLE DSVTSNLFRL LTRDLKCVAS GDQCV
• Biology activity: Biological activity was determined by its ability to activate STAT following receptor - ligand interaction.
• Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
• Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Wysyłka i przechowywanie:

The lyophilized IFN lambda 2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IFN lambda 2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IFN lambda 2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Inne:

This product is for research use only.