sCD34 Recombinant Protein

CD34 is a highly glycosylated type I membrane protein that is selectively expressed on hematopoietic stem cells and vascular endothelium. It has been widely used as a molecular marker for the identification, isolation, and manipulation of hemopoietic stem cells and progenitors. CD34 can function as a regulator of hemopoietic cell adhesion by mediating the attachment of stem cells to bone marrow stromal cells or other bone marrow components. The full length human CD34 is a 385 amino acid protein, consisting of a 31 amino acid signal sequence, a 74 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain and a 259 amino acid extracellular domain. Recombinant human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein.

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: N/A
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: N/A
• Concentration: N/A
• NCBI official symbol: CD34
• Accession #: NP_001020280.1
• Protein GI: 68342038
• NCBI gene ID#: 947
• NCBI official full name: CD34 molecule
• NCBI organism: Homo sapiens
• Peptide sequence: LDNNGTATPE LPTQGTFSNV STNVSYQETT TPSTLGSTSL HPVSQHGNEA TTNITETTVK FTSTSVITSV YGNTNSSVQS QTSVISTVFT TPANVSTPET TLKPSLSPGN VSDLSTTSTS LATSPTKPYT SSSPILSDIK AEIKCSGIRE VKLTQGICLE QNKTSSCAEF KKDRGEGLAR VLCGEEQADA DAGAQVCSLL LAQSEVRPQC LLLVLANRTE ISSKLQLMKK HQSDLKKLGI LDFTEQDVAS HQSYSQKT
• SWISSPROT #: P28906
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: CHO cells
• Species: Human
• By Source: CHO Cells
• By Species: Human
• Fusion tag: N/A
• Sequence: LDNNGTATPE LPTQGTFSNV STNVSYQETT TPSTLGSTSL HPVSQHGNEA TTNITETTVK FTSTSVITSV YGNTNSSVQS QTSVISTVFT TPANVSTPET TLKPSLSPGN VSDLSTTSTS LATSPTKPYT SSSPILSDIK AEIKCSGIRE VKLTQGICLE QNKTSSCAEF KKDRGEGLAR VLCGEEQADA DAGAQVCSLL LAQSEVRPQC LLLVLANRTE ISSKLQLMKK HQSDLKKLGI LDFTEQDVAS HQSYSQKT
• Biology activity: Endotoxin level is less than 0.1 ng per µg (1EU/µg).
• Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.

Wysyłka i przechowywanie:

The lyophilized sCD34 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted sCD34 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing sCD34 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Inne:

This product is for research use only.