BCMA Recombinant Protein

BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain. Recombinant soluble BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein.

Specyfikacja/Zawartość:

• Tested Applications: N/A
• Applications: N/A
• Predicted Molecular Weight: N/A
• Physical state: Lyophilized
• Buffer: N/A
• Concentration: N/A
• NCBI official symbol: TNFRSF17
• Accession #: NP_001183.2
• Protein GI: 23238192
• NCBI gene ID#: 608
• NCBI official full name: tumor necrosis factor receptor superfamily, member 17
• NCBI organism: Homo sapiens
• Peptide sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
• SWISSPROT #: Q02223
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: E. coli
• Species: Human
• By Source: E. Coli
• By Species: Human
• Fusion tag: N/A
• Sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
• Biology activity: N/A
• Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
• Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Wysyłka i przechowywanie:

The lyophilized BCMA recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted BCMA is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing BCMA recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Inne:

This product is for research use only.