Ładowanie zawartość koszyka...
Anti-LDLR antibody
Numer katalogowy: 665-STJ117194
Kategoria produktu: Biznes i przemysł > Badania naukowe i laboratoryjne
Sprzedawca:Gentaur
Rozmiar:
100 µl
Dostępność:
Dostępny
Cena:
2432.25 PLN*
* Cena orientacyjna netto,
zawierająca również szacunkowy koszt transportu.
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The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
Specyfikacja/Zawartość:
- Clonality: Polyclonal
- Host: Rabbit
- Conjugation: Unconjugated
- Applications: WB
- Reactivity: Human,Mouse
- Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Purification: Affinity purification
- Clone: NA
- Concentration: NA
- Gene: LDLR
- Immunogen: A synthetic peptide corresponding to a sequence within amino acids 800 to the C-terminus of human LDLR (NP_000518.1).
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