E6446
Kategoria produktu: Biznes i przemysł > Badania naukowe i laboratoryjne
Sprzedawca:Gentaur
E6446 is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD)[1][2][3].
Specyfikacja/Zawartość:
- CAS number: 1219925-73-1
- Formula: C27H35N3O3
- Solubility: 10 mM in DMSO
- SMILES: C1(C2=CC=C(OCCCN3CCCC3)C=C2)=NC4=CC=C(OCCCN5CCCC5)C=C4O1
- Molecular Weight: 449.59
- Applications: COVID-19-immunoregulation
Inne:
For research use only. Not to be used for human or animal treatment or consumption.
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