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Caspase12 Polyclonal Antibody
Numer katalogowy: 772-BT-AP01196-100ul
Kategoria produktu: Biznes i przemysł > Badania naukowe i laboratoryjne
Sprzedawca:Gentaur
Rozmiar:
100ul
Dostępność:
Na zamówienie
Cena:
0.01 PLN*
* Zapytaj o ofertę, aby otrzymać aktualną ofertę w 24h.
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for CASP12.
Dodatkowe informacje:
WB, IHC-p, ELISA
Specyfikacja/Zawartość:
Human
Wysyłka i przechowywanie:
-20°C for one year
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