Anti-Human Complement Factor D Antibody

Complement Factor D, also known as adipsin, is a serine protease that catalyzes the initial proteolytic step in the alternative pathway of complement. It is an exceptionally specific protease and the only known protein substrate is factor B in complex with C3.3 Factor D protease activity is regulated by reversible conformational changes, which differs from the majority of serine proteases whose regulation involves either activation by processing of the zymogens or inactivation by binding of the inhibitors.

Specyfikacja/Zawartość:

• Gene name: Complement Factor D
• Host: Mouse
• Label: None
• Clone: (#4S49)
• Isotype: IgG2
• Applications: Capture Ab
• Species Reactivity/Origin species: Human
• Antigen: Human recombinant Complement Factor D (Adipsin)
• Purification method: Protein G chromatography
• Reconstitution Buffer: PBS
• Buffer: PBS
• Additives/Stabilizer: None
• Form: lyophilized
• Storage: Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
• Reconstitution tips: Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
• NCBI GeneID: 1675
• Accession Number Protein: NP_001919.2
• Accession Numberm RNA: NM_001928.2
• Uniprot: P00746
• Chromosomal location: 19p13.3

Inne:

For research use only.