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1-Hydroxy-2,3,5-trimethoxyxanthone
Numer katalogowy: 931-TN2534-1g
Kategoria produktu: Biznes i przemysł > Badania naukowe i laboratoryjne
Sprzedawca:Gentaur
Rozmiar:
1g
Dostępność:
Na zamówienie
Cena:
0.01 PLN*
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1-Hydroxy-2,3,5-trimethoxyxanthone
Dodatkowe informacje:
- SMILES: COc1cc2oc3c(OC)cccc3c(=O)c2c(O)c1OC
- Formula: C16H14O6
Specyfikacja/Zawartość:
- Purity: 0.98
- CAS#: 22804-49-5
- Molecular Weight: 302.28
- Bioactivity: 1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type voltage-operated Ca(2+) channels
- a minor contribution to the effects of HM-1 may be related to inhibition of the protein kinase C-mediated release of intracellular Ca(2+) stores. HM-1,at the concentration of 1 ug/mL, can effectively inhibit the osteoclast differentiation in a co-culture system with mouse osteoblastic calvarial cells and bone marrow cells
- it also can protect mice from the acute lung injury induced by ipopolysaccharide (LPS), which is relative to the increasing of IκB-α protein expression and the suppressing of inducible nitric oxide synthase and cyclooxygenase-Ⅱ protein expression.
Inne:
For research use only.
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