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Chlorin e6
Numer katalogowy: 931-T36466-1mg
Kategoria produktu: Biznes i przemysł > Badania naukowe i laboratoryjne
Sprzedawca:Gentaur
Rozmiar:
1mg
Dostępność:
Na zamówienie
Cena:
0.01 PLN*
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Chlorin e6
Dodatkowe informacje:
- SMILES: C(C(O)=O)C1=C2[C@@H](CCC(O)=O)[C@H](C)C(=N2)C=C3NC(C(C=C)=C3C)=CC4=NC(=CC=5NC1=C(C(O)=O)C5C)C(CC)=C4C
- Formula: C34H36N4O6
Specyfikacja/Zawartość:
- Purity: 0.98
- CAS#: 19660-77-6
- Molecular Weight: 596.67
- Bioactivity: Chlorin e6 (Ce6) is a second-generation photosensitizer with antitumor activity when used in conjunction with irradiation. In a mouse model of implanted fibrosarcoma, Ce6 (2.5-10 mg/kg, i.v. with irradiation at 50-200 J/cm2) led to complete tumor loss following varying levels of irradiation.[1] A formulation including Ce6 was tested in a Phase I clinical study for patients with bronchogenic early superficial squamous cell carcinoma with positive results (40 mg/m2, i.v. with laser irradiation at 100 J/cm2).[2] The same dosing paradigm in a Phase II clinical trial for early stage lung cancer patients led to a complete response in 82.9% of patients.[3] Ce6 has been examined as a nanotechnology drug delivery tool.[4]
Inne:
For research use only.
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