14,15-EE-5(Z)-E
Numer katalogowy: 931-T36150-1g
Kategoria produktu: Biznes i przemysł > Badania naukowe i laboratoryjne
Sprzedawca:Gentaur
Rozmiar:
1g
Dostępność:
Na zamówienie
Cena:
0.01 PLN*
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14,15-EE-5(Z)-E
Dodatkowe informacje:
- SMILES: CCCCC[C@@H]1O[C@@H]1CCCCCCC\C=C/CCCC(O)=O
- Formula: C20H36O3
Specyfikacja/Zawartość:
- Purity: 0.98
- CAS#: 519038-92-7
- Molecular Weight: 324.505
- Bioactivity: Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 μM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.
Inne:
For research use only.
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