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Jacaric Acid
Numer katalogowy: 931-T36099-50mg
Kategoria produktu: Biznes i przemysł > Badania naukowe i laboratoryjne
Sprzedawca:Gentaur
Rozmiar:
50mg
Dostępność:
Na zamówienie
Cena:
0.01 PLN*
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Jacaric Acid
Dodatkowe informacje:
- SMILES: CCCCC\C=C/C=C/C=C\CCCCCCC(O)=O
- Formula: C18H30O2
Specyfikacja/Zawartość:
- Purity: 0.98
- CAS#: 28872-28-8
- Molecular Weight: 278.436
- Bioactivity: Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Structurally, it is an 18-carbon ω-6 triene isomer of γ-linolenic acid . Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 μM). It increases the production of reactive oxygen species, and cytotoxicity is abolished by the antioxidant α-tocopherol, suggesting that apoptosis results from oxidative stress. Jacaric acid is metabolized in vivo to conjugated linoleic acid , which is also cytotoxic to cancer cells. Jacaric acid inhibits cyclooxygenase-1 in vitro (Ki = 1.7 μM) and, with long term feeding, decreases stearoyl-CoA desaturase expression and activity in mice.
Inne:
For research use only.
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