Cytokeratin 13 Antibody / KRT13
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Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.
Dodatkowe informacje:
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Specyfikacja/Zawartość:
Human
Wysyłka i przechowywanie:
Store the Cytokeratin 13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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