Serum Albumin Recombinant Protein
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serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80% of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
Specyfikacja/Zawartość:
- Tested Applications: WB
- Applications: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.8 kDa. The protein migrates as 65-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Predicted Molecular Weight: 67.8 kDa
- Physical state: Lyophilized
- Buffer: PBS, pH7.4
- Concentration: N/A
- NCBI official symbol: Alb
- Accession #: NP_033784.2
- Protein GI: N/A
- NCBI gene ID#: 11657
- NCBI official full name: albumin
- NCBI organism: Mus musculus
- Peptide sequence: N/A
- SWISSPROT #: P07724
- Background Reference 1: Carter D.C., et al., 1989, Science 244:1195-1198.
- Background Reference 2: Minchiotti L., et al., Eur. 2001, J. Biochem. 268:344-352.
- Background Reference 3: Minchiotti L., et al., 1992, Biochim. Biophys. Acta 1119:232-238.
- Background Reference 4: N/A
- Background Reference 5: N/A
- Source: HEK293 cells
- Species: Mouse
- By Source: Human Cells
- By Species: Mouse
- Fusion tag: His Tag
- Sequence: Glu 25 - Ala 608
- Biology activity: N/A
- Purity: >95% as determined by SDS-PAGE.
Wysyłka i przechowywanie:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Inne:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
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