Rhesus macaque CD155 / PVR Recombinant Protein

CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.

Specyfikacja/Zawartość:

• Tested Applications: E, WB
• Applications: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.3 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Predicted Molecular Weight: 36.3 kDa
• Physical state: Lyophilized
• Buffer: PBS, pH7.4
• Concentration: N/A
• NCBI official symbol: PVR
• Accession #: NP_001036851.1
• Protein GI: N/A
• NCBI gene ID#: 712851
• NCBI official full name: poliovirus receptor
• NCBI organism: Macaca mulatta
• Peptide sequence: N/A
• SWISSPROT #: N/A
• Background Reference 1: Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47): 18284-18289.
• Background Reference 2: Maier MK., et al., 2007, European Journal of Immunology, 37 (8): 2214-2225.
• Background Reference 3: He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1): 79-84.
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: HEK293 cells
• Species: Rhesus monkey
• By Source: Human Cells
• By Species: Other
• Fusion tag: His Tag
• Sequence: Asp 28 - Asn 343
• Biology activity: N/A
• Purity: >90% as determined by SDS-PAGE.

Wysyłka i przechowywanie:

Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Inne:

Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.