SARS-CoV-2 (COVID-19) Full-Length Eta Variant (B.1.525, UK) Spike Recombinant Protein

All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose. To help the sciencific community to combat these mutants ProSci offers the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent. This is the SPIKE protein of the mutant strain B.1.525.

Specyfikacja/Zawartość:

• Tested Applications: E
• Applications: This recombinant protein can be used for ELISA assays, Ligand binding assays (e.g. SPR), Biochemical and biophysical analyses. For research use only.
• Predicted Molecular Weight: 1286 amino acids (including Rho1D4 tag and linker)
• 142114 Da
• Physical state: Liquid
• Buffer: 20 mM Hepes pH 7.5
• 150 mM NaCl, 0.001 % LMNG
• Concentration: batch dependent
• NCBI official symbol: S
• Accession #: N/A
• Protein GI: N/A
• NCBI gene ID#: 43740568
• NCBI official full name: surface glycoprotein
• NCBI organism: Severe acute respiratory syndrome coronavirus 2
• Peptide sequence: Full-length sequence (aa 1 – 1273), del 69-70
• del 144
• Q52R
• E484K
• Q677H
• F888L
• furin cleavage site “RRAR” mutated to “GSAG”
• K986P
• V987P
• C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence
• SWISSPROT #: P0DTC2
• Background Reference 1: N/A
• Background Reference 2: N/A
• Background Reference 3: N/A
• Background Reference 4: N/A
• Background Reference 5: N/A
• Source: HEK293 cells
• Species: SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein
• By Source: Human Cells
• By Species: Other
• Fusion tag: C-terminal Rho1D4
• Sequence: Full-length sequence (aa 1 – 1273), del 69-70
• del 144
• Q52R
• E484K
• Q677H
• F888L
• furin cleavage site “RRAR” mutated to “GSAG”
• K986P
• V987P
• C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence
• Biology activity: not determined
• Purity: >98% as determined by SDS-PAGE, see Fig. 1 A and B. PureCube Rho1D4 Agarose.

Wysyłka i przechowywanie:

–80°C. Avoid freeze-thaw cycles

Inne:

Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.