MCP-1 Recombinant Protein
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The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Specyfikacja/Zawartość:
- Tested Applications: N/A
- Applications: N/A
- Predicted Molecular Weight: N/A
- Physical state: Lyophilized
- Buffer: N/A
- Concentration: N/A
- NCBI official symbol: Ccl2
- Accession #: NP_035463.1
- Protein GI: 6755430
- NCBI gene ID#: 20296
- NCBI official full name: chemokine (C-C motif) ligand 2
- NCBI organism: Mus musculus
- Peptide sequence: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
- SWISSPROT #: P10148
- Background Reference 1: N/A
- Background Reference 2: N/A
- Background Reference 3: N/A
- Background Reference 4: N/A
- Background Reference 5: N/A
- Source: E. coli
- Species: Murine
- By Source: E. Coli
- By Species: Mouse
- Fusion tag: N/A
- Sequence: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
- Biology activity: Biological activity was determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0 - 20.0 ng/mL.
- Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Wysyłka i przechowywanie:
The lyophilized MCP-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted MCP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing MCP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Inne:
This product is for research use only.
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