Anti-CASP4 antibody

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Specyfikacja/Zawartość:

• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Applications: WB,IHC
• Reactivity: Human,Mouse,Rat
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purification: Affinity purification
• Clone: NA
• Concentration: NA
• Gene: NA
• Immunogen: Recombinant protein of mouse CASP4