Opis Produktu:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human BD-1 is a 3.9 kDa protein containing 36 amino acid residues.
Specyfikacja/Zawartość:
- category: Recombinant Proteins
- gene name: DEFB1
- contents: Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
- uniprot_id: P60022
- form: Solid
- white powder or thin/invisible film
- purification: NA
- applications: Cell Culture
- subcellular_localization: Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203). .
- source: E. Coli
Wysyłka i przechowywanie:
Store in -20°c for long term storage. After reconstitution, store in 4°c for short term usage within a few days. Avoid freeze-thaw cycles.
Inne:
this product is available in other size, Various Sizes, please contact us for more information.
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