Recombinant Murine IL-4 Protein

IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.

Specyfikacja/Zawartość:

• category: Recombinant Proteins
• gene name: Il4
• contents: Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
• uniprot_id: P07750
• form: Solid
• white powder or thin/invisible film
• purification: Above 98% as determined by SDS-PAGE Analysis.
• applications: Cell Culture
• subcellular_localization: Secreted.
• source: E. Coli

Wysyłka i przechowywanie:

Store in -20°c for long term storage. After reconstitution, store in 4°c for short term usage within a few days. Avoid freeze-thaw cycles.

Inne:

this product is available in other size, Various Sizes, please contact us for more information.