ELISA kit for Human Angiotensin I (ANG-1)

Quantitative sandwich ELISA for measuring Human Angiotensin I (ANG-1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Dodatkowe informacje:

Angiotensin I is formed by the action of renin on angiotensinogen. Renin is produced in the kidneys in response to both decreased intra-renal blood pressure at the juxtaglomerular cells, or decreased delivery of Na+ and Cl- to the macula densa. If more Na+ is sensed, renin release is decreased.Renin cleaves the peptide bond between the leucine (Leu) and valine (Val) residues on angiotensinogen, creating the ten amino acid peptide (des-Asp) angiotensin I .Angiotensin I appears to have no biological activity and exists solely as a precursor to angiotensin 2.Angiotensin I is converted to angiotensin II through removal of two terminal residues by the enzyme Angiotensin-converting enzyme (ACE, orkinase), which is found predominantly in the capillaries of the lung. ACE is actually found all over the body, but has its highest density in the lung due to the high density of capillary beds there. Angiotensin II acts as an endocrine, autocrine/paracrine, and intracrine hormone.

Specyfikacja/Zawartość:

• Reactivity: Human
• Sample types: serum, whole blood, plasma and other biological fluids
• Detection range: Please inquire
• Sensitivity: Please inquire Quantitative Sandwich ELISA
• Method of detection: Colorimetric

Wysyłka i przechowywanie:

All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).

Inne:

This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.