ELISA kit for Human Linker for activation of T cell (LAT)

Quantitative sandwich ELISA for measuring Human Linker for activation of T cell (LAT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Dodatkowe informacje:

Linker of Activated T cells also known as LAT is a protein which is encoded by the LAT gene. Alternative splicing results in multiple transcript variants encoding different isoforms. The protein encoded by this gene is phosphorylated by ZAP70/SYK protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts (also known as glycosphingolipid-enriched microdomains or GEMs) and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement.

Specyfikacja/Zawartość:

• Reactivity: Human
• Sample types: serum, whole blood, plasma and other biological fluids
• Detection range: Please inquire
• Sensitivity: Please inquire Quantitative Sandwich ELISA
• Method of detection: Colorimetric

Wysyłka i przechowywanie:

All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).

Inne:

This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.