Human Glycogen phosphorylase, muscle form (PYGM) ELISA Kit

This Human Glycogen phosphorylase, muscle form (PYGM) ELISA Kit employs a two-site sandwich ELISA to quantitate PYGM.

Dodatkowe informacje:

Mutations in the muscle isoform of glycogen phosphorylase (PYGM) are associated with McArdle disease (glycogen storage disease type V). More than 65 mutations in the PYGM gene that lead to McArdle disease have been identified to date.Gautron et al. (1987) isolated muscle phosphorylase cDNA clones from a human cDNA library. Northern blot experiments revealed 1 specific mRNA of 3.4 kb found uniquely in tissues expressing muscle phosphorylase. The muscle glycogen phosphorylase protein comprises 842 amino acids (Kubisch et al., 1998).Burke et al. (1987) determined the intron/exon structure of the PYGM gene. Kubisch et al. (1998) provided a revised genomic structure for the PYGM gene, which contains 20 exons.

Specyfikacja/Zawartość:

• Reactivity: Human
• Sample types: serum, whole blood, plasma and other biological fluids
• Detection range: Please inquire
• Sensitivity: Please inquire Quantitative Sandwich ELISA
• Method of detection: Colorimetric

Wysyłka i przechowywanie:

Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.

Inne:

This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.