ELISA kit for Rat Dihydropyrimidine dehydrogenase (DPYD)
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Quantitative sandwich ELISA for measuring Rat Dihydropyrimidine dehydrogenase (DPYD) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Dodatkowe informacje:
Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation. It is the initial and rate-limiting step in pyrimidine catabolism. It catalyzes the reduction of uracil and thymine. It is also involved in the degradation of the chemotherapeutic drugs 5-fluorouracil and Tegafur-uracil.The sequence of the gene suggested that DPD has at least 3 distinct domains: a possible NADPH binding site and FAD-binding site in the N terminus, 2 motifs of putative iron/sulfur-binding sites near the C terminus, and a peptide domain corresponding to the uracil-binding site. Expression of the pig enzyme in E. coli catalyzed the reduction of uracil, thymine, and 5-fluorouracil (5FU) with kinetics approximating those published for the enzyme purified from mammalian liver.
Specyfikacja/Zawartość:
- Reactivity: Rat
- Sample types: serum, whole blood, plasma and other biological fluids
- Detection range: Please inquire
- Sensitivity: Please inquire Quantitative Sandwich ELISA
- Method of detection: Colorimetric
Wysyłka i przechowywanie:
All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
Inne:
This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.
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