ELISA kit for Rat Protein kinase C (PKC)
Gentaur
Mogą Cię zainteresować
Quantitative sandwich ELISA for measuring Rat Protein kinase C (PKC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Dodatkowe informacje:
Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family. PKC enzymes in turn are activated by signals such as increases in the concentration of diacylglycerol (DAG) or calcium ions (Ca2+).Hence PKC enzymes play important roles in several signal transduction cascades. The PKC family consists of fifteen isozymes in humans. They are divided into three subfamilies, based on their second messenger requirements: conventional (or classical), novel, and atypical.Conventional (c)PKCs contain the isoforms ?, ?I, ?II, and ?. These require Ca2+, DAG, and a phospholipid such as phosphatidylserine for activation. Novel (n)PKCs include the ?, ?, ?, and ? isoforms, and require DAG, but do not require Ca2+ for activation. Thus, conventional and novel PKCs are activated through the same signal transduction pathway as phospholipase C. On the other hand, atypical (a)PKCs (including protein kinase M? and ? / ? isoforms) require neither Ca2+ nor diacylglycerol for activation. The term "protein kinase C" usually refers to the entire family of isoforms.
Specyfikacja/Zawartość:
- Reactivity: Rat
- Sample types: serum, whole blood, plasma and other biological fluids
- Detection range: Please inquire
- Sensitivity: Please inquire Quantitative Sandwich ELISA
- Method of detection: Colorimetric
Wysyłka i przechowywanie:
All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
Inne:
This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.
0 opinie o ELISA kit for Rat Protein kinase C (PKC)